Jason L. Hornick, M.D., Ph.D. Expert Series – Practical Soft Tissue Pathology: A Comprehensive and Contemporary Update

CME Activity Description

Expert Series

Practical Soft Tissue Pathology: A Comprehensive and Contemporary Update

Jason L. Hornick, M.D., Ph.D. Expert Series – Practical Soft Tissue Pathology: A Comprehensive and Contemporary Update This accredited Continuing Medical Education (CME) activity provides a comprehensive and practical update in soft tissue pathology, with a strong emphasis on a pattern-based diagnostic approach and real-world sign-out challenges encountered in daily practice.

Target Audience

This program is primarily designed for:

• Practicing pathologists

• Surgical pathologists

• Pathologists with a special interest in soft tissue tumors and sarcoma diagnostics

Educational Objectives

Upon completion of this CME activity, participants will be able to:

• Apply a pattern-based approach to the differential diagnosis of soft tissue tumors

• Discuss the differential diagnosis of cutaneous mesenchymal tumors

• Describe the key histologic features of pleomorphic soft tissue tumors

• Recognize histologic and genetic subtypes of gastrointestinal stromal tumors (GIST)

• Apply a pattern-based diagnostic approach to vascular and nerve sheath tumors

• Utilize immunohistochemistry effectively in the diagnosis of soft tissue tumors

Educational Preparation

No special educational preparation is required for participation in this CME activity.

Faculty

Jason L. Hornick, M.D., Ph.D.
Director of Surgical Pathology and Immunohistochemistry
Brigham and Women’s Hospital
Professor of Pathology
Harvard Medical School
Boston, Massachusetts

Course Content / Lecture Titles

Core Foundations

1. Introduction to Soft Tissue Pathology: The New 2026 WHO Classification, Grading, and a Pattern-Based Approach

Pattern-Based Diagnostic Categories

2. Spindle Cell Tumors of Adults, Part I: Differential Diagnosis and Best Markers

3. Spindle Cell Tumors of Adults, Part II: Differential Diagnosis and Best Markers

4. Round Cell Sarcomas: Histologic Clues and Ancillary Testing

5. Pleomorphic Sarcomas: It Is Easier Than You Think!

6. Myxoid Tumors of Skin and Soft Tissue: From Benign to Malignant

7. Epithelioid Tumors: Diagnostic Challenges and How to Prevent Disaster

Site-Specific and Lineage-Based Tumors

8. Cutaneous Mesenchymal Tumors: What’s New?

9. Gastrointestinal Mesenchymal Tumors: What Do We Need to Know?

10. Vascular Tumors: Vasformative and Not So Much

11. Nerve Sheath Tumors: Key Features and Problems

Regional Pathology

12. Mesenchymal Tumors of the Head and Neck: Clues and Pitfalls

13. Mesenchymal Tumors of the Head and Neck: Clues and Pitfalls (Advanced / Extended Session)